Publicaties

    • 2024/2025

      • Schuijt E, Scherr D, Plank G, Schotten U, Heijman J. Evolution in electrophysiology 100 years after Einthoven: translational and computational innovations in rhythm control of atrial fibrillation. Europace. 2024 Dec 26;27(1):euae304. DOI: 10.1093/europace/euae304. PMID: 39729032; PMCID: PMC11707389.
      • Heijman J, Dobrev D. Spexin Hormone Signaling and Atrial Fibrillation: The Knowns and Unknowns. Circulation. 2024 Jul 9;150(2):128-131. DOI: 10.1161/CIRCULATIONAHA.124.070016. Epub 2024 Jul 8. PMID: 38976612; PMCID: PMC11232924.
      • Cluitmans MJM, Plank G, Heijman J. Digital twins for cardiac electrophysiology: state of the art and future challenges. Herzschrittmacherther Elektrophysiol. 2024 Jun;35(2):118-123. DOI: 10.1007/s00399-024-01014-0. Epub 2024 Apr 12. PMID: 38607554; PMCID: PMC11161534.
      • Saljic A, Heijman J. P2X7 receptors: central drivers of the neurocardiac link between atrial fibrillation and depression? Europace. 2024 Feb 1;26(2):euae023. DOI: 10.1093/europace/euae023. PMID: 38261750; PMCID: PMC10873697.
      • Trayanova NA, Lyon A, Shade J, Heijman J. Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation. Physiol Rev. 2024 Jul 1;104(3):1265-1333. DOI: 10.1152/physrev.00017.2023. Epub 2023 Dec 28. PMID: 38153307; PMCID: PMC11381036.
      • Jonathan P. Piccini, M.D., M.H.S., Manesh R. Patel, M.D., Jan Steffel, M.D., Keith Ferdinand, M.D., Isabelle C. Van Gelder, M.D., Ph.D., Andrea M. Russo, M.D., Chang-Sheng Ma, M.D., Shaun G. Goodman, M.D., Jonas Oldgren, M.D., Ph.D., Christopher Hammett, M.B., Ch.B., M.D., Renato D. Lopes, M.D., Ph.D., Masaharu Akao, M.D., Ph.D., Raffaele De Caterina, M.D., Ph.D., Paulus Kirchhof, M.D., Diana A. Gorog, M.D., Ph.D., Martin Hemels, M.D., Michiel Rienstra, M.D., W. Schuyler Jones, M.D., Josephine Harrington, M.D., Gregory Y.H. Lip, M.D.  Stephen J. Ellis, Ph.D., Frank W. Rockhold, Ph.D., Christoph Neumann, Ph.D., John H. Alexander, M.D., M.H.S., Thomas Viethen, M.D., M.H.B.A., James Hung, M.D., Rosa Coppolecchia, D.O., M.P.H., Hardi Mundl, M.D., and Valeria Caso, M.D., Ph.D., for the OCEANIC-AF Steering Committee and Investigators, Asundexian versus Apixaban in Patients with Atrial Fibrillation, N Engl J Med 2025;392:23-32,PMID: 39225267 DOI: 10.1056/NEJMoa2407105
      • Neda Khalilian Ekrami, Dawid K. Baron, Emelia J. Benjamin, Bart A. Mulder, Isabelle C. Van Gelder & Michiel Rienstra, Participation of women in clinical studies of atrial fibrillation in the Northern Netherlands, Neth Heart J 32, 326–331 (2024), PMID: 39105898 DOI: 10.1007/s12471-024-01887-3
      • Shinwan Kany, Sean J Jurgens, Joel T Rämö, Ingrid E Christophersen, Michiel Rienstra, Mina K Chung, Morten S Olesen, Michael J Ackerman, Elizabeth M McNally, Christopher Semsarian, Renate B Schnabel, Arthur A M Wilde, Emelia J Benjamin, Heidi L Rehm, Paulus Kirchhof, Connie R Bezzina, Dan M Roden, M Benjamin Shoemaker, Patrick T Ellinor, Genetic testing in early-onset atrial fibrillation, 
        eurheartj, PMID: 39028637 DOI: 10.1093/eurheartj/ehae298
      • Habibi Z, Verhaert DVM, Betz K, Hermans BJM, Winters J, Philippens SAM, Chaldoupi SM, Maesen B, Maessen JG, Isaacs A, Westra SW, Nijveldt R, Gillet L, Wienhues-Thelen UH, Koehler M, Zeemering S, Vernooy K, Linz D, Schotten U. Association of atrial fibrillation burden and clinical profile with blood biomarkers: Results from the ISOLATION Ablation Cohort. Heart Rhythm O2. 2025 Feb 28;6(5):661-670. Doi: 10.1016/j.hroo.2025.02.017. PMID: 40496590; PMCID: PMC12147586.
      • Giammarino L, Matas L, Alerni N, Horváth A, Vashanthakumar V, Nimani S, Barbieri M, Bains S, Lopez R, Louradour J, Ördög B, Hof T, Maguy A, Conte G, Auricchio A, Schotten U, Odening KE. Sex and sex hormonal regulation of the atrial inward rectifier potassium current (IK1): insights into potential pro-arrhythmic mechanisms. Cardiovasc Res. 2025 Apr 24:cvaf074. Doi: 10.1093/cvr/cvaf074. Epub ahead of print. PMID: 40272446.
      • van Deutekom C, van de Lande ME, Rama R, Nguyen BO, Tieleman RG, Weberndörfer V, Hemels MEW, de Melis M, Schotten U, Linz D, Crijns HJGM, van Gelder IC, Rienstra M; RACE V Investigators. Multimorbidity Is Associated With Symptom Severity and Disease Progression in Patients with Paroxysmal Atrial Fibrillation-Data From the RACE V Study. J Am Heart Assoc. 2025 Mar 4;14(5):e034514. Doi: 10.1161/JAHA.123.034514. Epub 2025 Feb 26. PMID: 40008502; PMCID: PMC12132691.
      • Isaacs A, Zeemering S, Winters J, Batlle M, Bidar E, Boukens B, Casadei B, Chua W, Crijns HJGM, Fabritz L, Guasch E, Hatem SN, Hermans B, Kääb S, Kawczynski M, Maesen B, Maessen J, Mont L, Sinner MF, Wakili R, Verheule S, Kirchhof P, Schotten U, Stoll M. Lateral Atrial Expression Patterns Provide Insights into Local Transcription Disequilibrium Contributing to Disease Susceptibility. Circ Genom Precis Med. 2025 Feb;18(1):e004594. 
        Doi: 10.1161/CIRCGEN.124.004594. Epub 2025 Jan 23. PMID: 39846178.
      • Hermans BJM, Özgül O, Wolf M, Marques VG, van Hunnik A, Verheule S, Chaldoupi SM, Linz D, El Haddad M, Duytschaever M, Bonizzi P, Vernooy K, Knecht S, Zeemering S, Schotten U. Selecting repetitive focal and rotational activation patterns with the highest probability of being a source of atrial fibrillation. J Mol Cell Cardiol Plus. 2024 Feb 3;7:100064. Doi: 10.1016/j.jmccpl.2024.100064. PMID: 39802439; PMCID: PMC11708417.
      • Marques VG, Gharaviri A, Özgül O, Pezzuto S, Auricchio A, Bonizzi P, Zeemering S, 
        Schotten U. A novel sequential endocardial mapping strategy for locating atrial 
        fibrillation sources based on repetitive conduction patterns: An in-silico study. J Mol Cell Cardiol Plus. 2024 Feb 22;7:100065. Doi: 10.1016/j.jmccpl.2024.100065. PMID: 39802438; 
        PMCID: PMC11708244.
      • Schotten U, Goette A, Verheule S. Translation of pathophysiological mechanisms of atrial fibrosis into new diagnostic and therapeutic approaches. Nat Rev Cardiol. 2025 Apr;22(4):225-240. Doi: 10.1038/s41569-024-01088-w. Epub 2024 Oct 23. 
        PMID: 39443702.
      • Gilbers MD, Kawczynski MJ, Bidar E, Maesen B, Isaacs A, Winters J, Linz D, Rienstra M, van Gelder I, Maessen JG, Schotten U. Determinants and impact of postoperative atrial fibrillation burden during 2.5 years of continuous rhythm monitoring after cardiac surgery: Results from the RACE V prospective cohort study. Heart Rhythm. 
        2025 Mar;22(3):647-660. Doi: 10.1016/j.hrthm.2024.08.014. 
        Epub 2024 Aug 8. PMID: 39121980.
      • Ozgul O, Marques VG, Hermans BJ, van Hunnik A, Verheule S, Gharaviri A, Pezzuto S, Auricchio A, Schotten U, Bonizzi P, Zeemering S. High-Density and High-Coverage Composite Atrial Activation Maps: An In-Silico Validation Study. IEEE Trans Biomed Eng. 2025 Jan;72(1):79-89. Doi: 10.1109/TBME.2024.3439502. Epub 2025 Jan 15. PMID: 39106138.
      • Bijvoet GP, Hermans BJM, Linz D, Luermans JGLM, Maesen B, Nijveldt R, Mihl C, Vernooy K, Wildberger JE, Holtackers RJ, Schotten U, Chaldoupi SM. 
        Optimal Threshold and Interpatient Variability in Left Atrial Ablation Scar Assessment by Dark-Blood LGE CMR. JACC Clin Electrophysiol. 2024 Oct;10(10):2186-2197. 
        Doi: 10.1016/j.jacep.2024.05.017. Epub 2024 Jul 10. PMID: 39001763.
      • Ayagama T, Charles PD, Bose SJ, Boland B, Priestman DA, Aston D, Berridge G, Fischer R, Cribbs AP, Song Q, Mirams GR, Amponsah K, Heather L, Galione A, Herring N, Kramer H, Capel RA, Platt FM, Schotten U, Verheule S, Burton RAB. 
        Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation. iScience. 2024 Mar 28;27(6):109609. 
        Doi: 10.1016/j.isci.2024.109609. PMID: 38827406; PMCID: PMC11141153.
      • Winters J, Kawczynski MJ, Gilbers MD, Isaacs A, Zeemering S, Bidar E, Maesen B, Rienstra M, van Gelder I, Verheule S, Maessen JG, Schotten U. Circulating BMP10 Levels Associate With Late Postoperative Atrial Fibrillation and Left Atrial Endomysial Fibrosis. JACC Clin Electrophysiol. 2024 Jul;10(7 Pt 1):1326-1340. Doi: 10.1016/j.jacep.2024.03.003
        Epub 2024 Apr 1. PMID: 38639699.
      • Gilbers MD, Kawczynski MJ, Bidar E, Maesen B, Isaacs A, Winters J, Linz D, Rienstra M, van Gelder I, Maessen JG, Schotten U. Clinical Predictors of Device-Detected Atrial Fibrillation During 2.5 Years After Cardiac Surgery: Prospective RACE V Cohort. JACC Clin Electrophysiol. 2024 May;10(5):941-955. 
        Doi: 10.1016/j.jacep.2024.01.013. Epub 2024 Mar 13. PMID: 38483418.